Welcome to Appletree Biostatistics AG

Appletree Biostatistics AG is specialized in biostatistics and data management for clinical research (clinical trials phase I - IV, patient registries).

Services

  • Statistical planning
    • Study design (classical, adaptive, crossover etc.)
    • Sample size, power calculation, Randomization plans
    • Statistical Consulting, statistical parts of the study protocol, CRF-Design
  • Biostatistics
    • Statistical Analysis Plan (SAP), statistical report
    • Explorative and descriptive analyses (tables, figures, listings)
    • Inferential statistics (superiority, non-inferiority, equivalence)
    • Modeling (LME, GEE, Cox-Regression, Kaplan-Meier etc.)
    • Publications (methods & results)
  • Data management
    • Web-based eCRF / electronic data capture (EDC) including
      Patient Reported Outcome (PRO) with tablet PC
    • 21 CFR Part 11 compliant
    • Data entry (single / double data entry)
    • Coding (MedDRA, WHO_DD)

Expertise

Our team has extensive experience in data management and statistical analyses in clinical trials (Phase I-IV according to ICH/GCP), patient registries (e.g. as required by the BAG), experience programs and surveys for medicinal products and medical devices.

Company

Appletree Biostatistics AG was founded 1986 under the name of Brunner & Hess Software AG. Since 2014, they are a subsidiary of Appletree CI Group AG, a contract research organization (CRO) in Winterthur, Switzerland. 

For further information please visit our corporate website
www.appletree-cig.com

Publications

For a selection of publications visit our corporate website
www.appletree-cig.com.

News

Appletree CI Group was awarded “Most Innovative CRO Company 2015”
Click here to read more about it.

 

TRAINING: Introduction to European Medical Device Regulatory Affairs
Appletree CI Group is offering this compact series of trainings to provide an introduction to medical device regulatory affairs in Europe. Please find the details here.

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